Key result
In a Latin American registry of 770 patients receiving an ICD for secondary prevention, all-cause mortality was 16.9% over a mean follow-up of 27 months, with advanced age, male sex, NYHA class III/IV, and low ejection fraction as independent predictors of death.
Population
770 patients from 7 Latin American countries with antecedents of aborted sudden death or cardiac arrest due…
Design
Cohort
Follow-up
27 ± 25 months (range 1-113 months)
Authors
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Mortality predictors align with global data in this Chagas-prevalent cohort; extends secondary prevention evidence but leaves practice implications open pending randomized trials.
Observational (n=770)
Yes
In a Latin American registry of ICD recipients for secondary prevention, mortality rates were comparable to classic randomized trials despite a different distribution of underlying etiologies, notably a high prevalence of Chagas disease.
Dubner et al. (2005) conducted an observational in Aborted sudden cardiac death or cardiac arrest due to ventricular tachycardia/fibrillation (n=770). Implantable Cardioverter Defibrillator (ICD) was evaluated on Death from all causes. In a Latin American registry of 770 patients receiving an ICD for secondary prevention, all-cause mortality was 16.9% over a mean follow-up of 27 months, with advanced age, male sex, NYHA class III/IV, and low ejection fraction as independent predictors of death.
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