Key result
Retrospective analysis of 768 nonpolio enterovirus isolates from acute flaccid paralysis cases identified 13 EV71 strains, including the first C2 subgenogroup strain reported in mainland China.
The identification of a 1996 C2 subgenogroup strain of Enterovirus 71 reveals that multiple subgenogroups circulated in mainland China prior to 1998.
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Should not alter acute flaccid paralysis evaluation; extends pre-1998 EV71 subgenogroup diversity in China.
Human enterovirus 71 (EV71) is an important pathogen and it can cause hand, foot, and mouth disease (HFMD), herpangina, and severe neurological symptoms. There was no intensive surveillance of EV71 until May 2008, when HFMD was classified as a category C notifiable infectious disease by the Ministry
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Tao et al. (2012) conducted a letter in Acute flaccid paralysis / Enterovirus 71 infection (n=768). Enterovirus 71 surveillance was evaluated on Identification of EV71 subgenogroups. Retrospective analysis of 768 nonpolio enterovirus isolates from acute flaccid paralysis cases identified 13 EV71 strains, including the first C2 subgenogroup strain reported in mainland China.
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