Key result
Acute ethanol ingestion increased baseline heart rate and forearm blood flow but had no physiologically significant effect on beta-adrenoceptor responsiveness to isoprenaline or atropine.
Why the study?
Does acute ethanol ingestion affect beta-adrenoceptor-mediated circulatory responses to isoprenaline in normal male subjects?
Population
Normal male subjects (n=21 for isoprenaline responses, n=15 for atropine responses)
Comparison
Acute ethanol ingestion vs Orange juice alone
Design
Other
Follow-up
Acute
Authors
Loading...
Acute ethanol leaves beta-adrenoceptor responsiveness intact in healthy men; leaves open effects in cardiovascular disease or with chronic use.
Does acute ethanol ingestion affect beta-adrenoceptor-mediated circulatory responses to isoprenaline in normal male subjects?
Acute ethanol ingestion does not significantly alter beta-adrenoceptor responsiveness to isoprenaline in healthy men.
Lambie et al. (1985) studied Healthy volunteers (n=36). Ethanol vs. Orange juice was evaluated on Circulatory responses to isoprenaline and atropine (heart rate, forearm blood flow, blood pressure). Acute ethanol ingestion increased baseline heart rate and forearm blood flow but had no physiologically significant effect on beta-adrenoceptor responsiveness to isoprenaline or atropine.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: