Key result
Patients with paroxysmal atrial fibrillation had significantly higher left atrial longitudinal strain (15.7±12.0) compared to those with persistent (4.3±7.9) and permanent (5.8±7.8) atrial fibrillation.
Why the study?
Improved knowledge of atrial structure and function may enhance treatment response in AF, prompting evaluation of LA strain and its determinants across AF types.
Does left atrial longitudinal strain and its determinants differ among patients with paroxysmal, persistent, and permanent non-valvular atrial fibrillation?
Comparison
Paroxysmal vs persistent vs permanent AF
Design
Cross-sectional echocardiographic study
Authors
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LA strain reduction in persistent/permanent AF warrants interpretive caution; leaves open subtype-specific determinants and prospective outcome prediction.
Cross-Sectional (n=58)
No
Does left atrial longitudinal strain and its determinants differ among patients with paroxysmal, persistent, and permanent non-valvular atrial fibrillation?
Absolute Event Rate: 4.3% vs 15.7%
p-value: p=0.003
Left atrial longitudinal strain is significantly reduced in persistent and permanent atrial fibrillation compared to paroxysmal AF, with different clinical and echocardiographic determinants for each subtype.
Aleksandra et al. (2019) conducted a cross-sectional in Non-valvular Atrial Fibrillation (n=58). Persistent or permanent atrial fibrillation vs. Paroxysmal atrial fibrillation was evaluated on Left atrial longitudinal strain (LALS) (p=0.003). Patients with paroxysmal atrial fibrillation had significantly higher left atrial longitudinal strain (15.7±12.0) compared to those with persistent (4.3±7.9) and permanent (5.8±7.8) atrial fibrillation.
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