Key result
In a population without cardiac disease, women had significantly smaller left main coronary artery cross-sectional areas even after normalization for left ventricular mass compared to men.
Why the study?
Are there gender differences in coronary artery size normalized for left ventricular mass in individuals without cardiac disease?
Population
200 individuals without cardiac disease and with normal Doppler echocardiography, mean age 44 +/- 15 years…
Design
Cross-sectional
Loading...
May inform sex-specific CAD risk models; leaves open whether size thresholds alter management in women.
Cross-Sectional (n=200)
Single-blind
No
Are there gender differences in coronary artery size normalized for left ventricular mass in individuals without cardiac disease?
Absolute Event Rate: 7% vs 9%
p-value: p=<0.0001
Women without cardiac disease have intrinsically smaller coronary arteries than men, even after accounting for differences in left ventricular mass, which may contribute to gender-specific risks in coronary artery disease.
A 2001 study conducted a cross-sectional in Without cardiac disease (n=200). Female gender vs. Male gender was evaluated on Left main coronary artery cross-sectional area normalized for left ventricular mass (mm2/100 g) (p=<0.0001). In a population without cardiac disease, women had significantly smaller left main coronary artery cross-sectional areas even after normalization for left ventricular mass compared to men.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: