Key result
Multiple complex coronary plaques in ACS patients were associated with larger carotid IMT (P<0.0003) and interadventitial diameter (7.93 vs 7.48 mm, P<0.01) compared to solitary plaques.
Why the study?
Are multiple complex coronary plaques associated with positive carotid remodeling in patients with acute coronary syndrome?
Population
125 consecutive patients with acute coronary syndrome (ACS)
Comparison
Multiple complex coronary plaques identified by… vs Solitary complex coronary plaques (n=50)
Design
Cross-sectional
Authors
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Supports systemic vulnerability in ACS; hypothesis-generating and requires prospective validation before clinical use.
Observational (n=125)
Are multiple complex coronary plaques associated with positive carotid remodeling in patients with acute coronary syndrome?
p-value: p=<0.0003
In patients with ACS, the presence of multiple complex coronary plaques is associated with positive carotid remodeling, suggesting plaque vulnerability is a systemic process.
Kato et al. (2003) conducted an observational in Acute coronary syndrome (n=125). Multiple complex coronary plaques vs. Solitary complex coronary plaques was evaluated on Carotid intima-media thickness (IMT) (p=<0.0003). Multiple complex coronary plaques in ACS patients were associated with larger carotid IMT (P<0.0003) and interadventitial diameter (7.93 vs 7.48 mm, P<0.01) compared to solitary plaques.
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