Key result
Polycystic ovary syndrome was associated with delayed mean latency of sympathetic skin response compared with healthy controls, indicating autonomic dysfunction.
Why the study?
Do patients with polycystic ovary syndrome have altered autonomic nervous system function compared to healthy controls?
Case-Control (n=70)
Do patients with polycystic ovary syndrome have altered autonomic nervous system function compared to healthy controls?
Answers are grounded in this paper and cite their sources.
Patients with PCOS demonstrate both parasympathetic and sympathetic autonomic dysfunction, which can be detected using sympathetic skin response and R-R interval variation tests.
OBJECTIVE: To assess the autonomic system in patients with polycystic ovary syndrome (PCOS). MATERIALS AND METHODS: Thirty-seven adult patients with PCOS and 33 healthy controls were enrolled in the study. The electrophysiological assessments of the autonomic nervous system function were performed using sympathetic skin response and R-R interval variation tests. RESULTS: The mean latency of sympathetic skin response in PCOS patients was significantly delayed compared with the controls (p = 0.001). The mean amplitude of sympathetic skin response was significantly lower in comparison with the controls (p = 0.01). Mean R-R interval variation during deep breathing was also significantly delayed (p = 0.04). CONCLUSION: There are parasympathetic dysfunction and sympathetic dysfunction in patients with PCOS. This may be easily demonstrated with sympathetic skin response and R-R interval variation tests.
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Dağ et al. (2015) conducted a case-control in Polycystic ovary syndrome (n=70). Polycystic ovary syndrome vs. Healthy controls was evaluated on Mean latency of sympathetic skin response (p=0.001). Polycystic ovary syndrome was associated with delayed mean latency of sympathetic skin response compared with healthy controls, indicating autonomic dysfunction.
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