Key result
PCOS linked to ~3-fold higher COMPASS-31 scores versus controls, indicating early cardiac autonomic dysfunction.
Why the study?
Patients with PCOS are vulnerable to cardiac and metabolic comorbidities and sympathetic overactivity, but cardiac autonomic function requires assessment.
Does polycystic ovary syndrome affect cardiac autonomic function in women of reproductive age?
Population
30 female PCOS patients and 30 age-matched control females
Comparison
PCOS patients vs age-matched controls
Design
Case-control study
Authors
Loading...
May indicate early autonomic dysfunction in PCOS; hypothesis-generating and requires prospective confirmation before clinical adoption.
Case-Control (n=60)
No
Does polycystic ovary syndrome affect cardiac autonomic function in women of reproductive age?
Absolute Event Rate: 16.17% vs 5.18%
p-value: p=0.001808
Women with PCOS exhibit early signs of cardiac autonomic dysfunction, characterized by increased sympathetic drive and reduced vagal tone, independent of BMI.
Shrivastava et al. (2023) conducted a case-control in Polycystic Ovary Syndrome (PCOS) (n=60). Polycystic Ovary Syndrome vs. Healthy age-matched controls was evaluated on COMPASS-31 score (p=0.001808). Women with polycystic ovary syndrome had significantly higher COMPASS-31 scores (16.17 vs 5.18, p=0.0018) and LF/HF ratios compared to healthy controls, indicating early cardiac autonomic dysfunction.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: