Key result
Normal-weight women with PCOS and normal insulin resistance show similar HRV to healthy controls.
Why the study?
The cardiac autonomic functions of normal-weight women with PCOS are conflicting and need assessment of cardiac sympathovagal balance reactivity.
Does polycystic ovary syndrome alter cardiac sympathovagal balance and heart rate variability in normal-weight women?
Population
60 normal-weight women with PCOS and 60 age-matched healthy women with similar metabolic profile
Comparison
Normal-weight women with PCOS vs age-matched healthy women
Design
Case-control study analyzing heart rate variability
Authors
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Preserved HRV reactivity in normal-weight PCOS with normal HOMA-IR; leaves open whether obesity or insulin resistance drives autonomic changes reported elsewhere.
Case-Control (n=120)
Does polycystic ovary syndrome alter cardiac sympathovagal balance and heart rate variability in normal-weight women?
Normal-weight women with PCOS and normal insulin resistance do not exhibit altered cardiac sympathovagal balance compared to healthy controls.
Celal Kılıt (2017) conducted a case-control in Polycystic ovary syndrome (n=120). Polycystic ovary syndrome vs. Age-matched healthy women was evaluated on Time and frequency domain parameters of heart rate variability during rest, controlled breathing, and isometric handgrip exercise. Normal-weight women with polycystic ovary syndrome and normal insulin resistance had similar time and frequency domain parameters of heart rate variability compared to healthy controls.
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