Key result
Polycystic ovary syndrome linked to increased sympathetic modulation and a ~104% higher LF/HF ratio.
Why the study?
Does polycystic ovary syndrome alter autonomic nervous system modulation as measured by heart rate variability compared to healthy ovulatory women?
Population
Women with polycystic ovary syndrome (PCOS) and healthy ovulatory women with regular menstrual cycles
Design
Cohort
Authors
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Increased sympathetic HRV modulation in PCOS may signal autonomic imbalance; hypothesis-generating and should not yet change practice.
Observational
Does polycystic ovary syndrome alter autonomic nervous system modulation as measured by heart rate variability compared to healthy ovulatory women?
Absolute Event Rate: 1.49% vs 0.73%
p-value: p=.009
Women with PCOS exhibit increased sympathetic modulation compared to healthy controls, as measured by heart rate variability.
Ji et al. (2018) conducted an observational in Polycystic ovary syndrome. Polycystic ovary syndrome vs. Healthy ovulatory women with regular menstrual cycles was evaluated on LF/HF ratio (p=.009). Polycystic ovary syndrome was associated with increased sympathetic modulation, including a significantly higher LF/HF ratio (1.49 vs 0.73, P=0.009) compared to healthy ovulatory women.
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