Key result
A cardiovascular implantable electronic device may tolerate high-dose radiotherapy (60 Gy) during long-term follow-up in a patient with esophageal cancer.
Why the study?
There was a concern regarding radiotherapy for cancer patients with CIED due to potential device malfunction after radiotherapy, especially above a 5 Gy high-risk threshold.
Can cardiovascular implantable electronic devices tolerate high dose radiotherapy?
Case Report (n=1)
Can cardiovascular implantable electronic devices tolerate high dose radiotherapy?
This case report suggests that cardiovascular implantable electronic devices may tolerate radiotherapy doses significantly higher than the currently recommended 5 Gy threshold, particularly when the high dose is localized to the lead rather than the generator.
Cardiovascular disease was common in the clinic and cardiovascular implantable electronic devices (CIED) was one of the modalities for patients with cardiovascular disease with rate issues. There was a concern regarding radiotherapy for cancer patients with CIED due to potential CIED malfunction after radiotherapy in which a threshold of 5 Gy was considered as high risk according to the report by American Association of Physicists in Medicine [Med Phys 2019;46(12):e757-e788]. We had previously reported the short term (5 months) outcome of a case of cT1N0M0 esophageal squamous cell carcinoma with CIED treated with radiotherapy 60 Gy/30 Fx with CIED dose of 57.77 Gy at the lead of the CIED though the maximal dose at the CIED generator was 0.39 Gy [Therapeut Radiol Oncol 2013;20(3):235-242].
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Lin et al. (2021) conducted a case report in cT1N0M0 esophageal squamous cell carcinoma with CIED (n=1). Radiotherapy was evaluated on CIED malfunction. A cardiovascular implantable electronic device may tolerate high-dose radiotherapy (60 Gy) during long-term follow-up in a patient with esophageal cancer.
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