Key result
Strenuous running caused a significant decrease in cardiac glycogen to 2.66 mg/g followed by an extended period of supercompensation peaking at 9.01 mg/g at 4 hours postexercise.
Population
Male Long-Evans rats (normally active, caged, and fed)
Comparison
Moderate running or strenuous running vs Control level (no exercise)
Design
Preclinical
Follow-up
Up to 17 hours postexercise
Authors
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Does not support human exercise recommendations; leaves open cardiac glycogen responses to exercise intensity in clinical models.
Absolute Event Rate: 2.66% vs 4.09%
The severity of exercise in normal, fed rats determines the extent of cardiac glycogen depletion and the subsequent supercompensation pattern of repletion.
Segel et al. (1975) studied Normal, fed male Long-Evans rats. Strenuous running vs. Moderate running and average control level was evaluated on Cardiac glycogen levels. Strenuous running caused a significant decrease in cardiac glycogen to 2.66 mg/g followed by an extended period of supercompensation peaking at 9.01 mg/g at 4 hours postexercise.
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