Key result
The lymphocyte platelet ratio showed no significant correlation with Gensini scores in patients with coronary heart disease (average LPR 124.6 in severe vs 115.3 in mild atherosclerosis; p=0.107).
Why the study?
Lymphocyte platelet ratio is an inflammatory marker that can be used to identify coronary heart disease severity, but its correlation with Gensini scores needed determination.
Does the lymphocyte platelet ratio correlate with the Gensini score in patients with coronary heart disease?
Cross-Sectional (n=51)
Does the lymphocyte platelet ratio correlate with the Gensini score in patients with coronary heart disease?
The lymphocyte platelet ratio does not significantly correlate with angiographic severity of coronary heart disease as measured by the Gensini score.
The lymphocyte platelet ratio (LPR) is an inflammatory marker that can be used to identify the severity of coronary heart disease (CHD). This study aims to determine the correlation between the lymphocyte platelet ratio and Gensini scores in CHD patients. This research used correlative analytical research with a cross-sectional design . The sample was selected by consecutive sampling technique and obtained 51 respondents. The calculation of the LPR was carried out by dividing the number of platelets and lymphocytes in the volume unit of 10 3 /mm 3 . Meanwhile, the Gensini score assessment was carried out by multiplying the percentage of blockages and location of blockages based on the result of coronary angiography. Based on the Gensini score, the sample in this study was classified as mild atherosclerosis with the Gensini score <25 points, and severe atherosclerosis with the Gensini score ≥25 points. The data were analyzed using the Pearson correlation test. The result showed that the average LPR value in samples with severe atherosclerosis was 124.6 and 115.3 in mild atherosclerosis. Based on the result of statistical analysis using the Pearson test, the p-value was 0.107. It can be concluded that there is no significant correlation between the lymphocyte platelet ratio and Gensini scores in CHD patients.
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Muliana et al. (2020) conducted a cross-sectional in Coronary heart disease (n=51). Lymphocyte platelet ratio was evaluated on Correlation between lymphocyte platelet ratio and Gensini score (p=0.107). The lymphocyte platelet ratio showed no significant correlation with Gensini scores in patients with coronary heart disease (average LPR 124.6 in severe vs 115.3 in mild atherosclerosis; p=0.107).
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