Key result
Three children with COVID-19-related multisystem inflammatory syndrome presented with a spectrum of cardiac involvement, including myocarditis, cardiogenic shock, heart failure, and coronary changes.
Why the study?
Cardiac involvement as a complication of SARS-CoV-2 infection in children is a relatively new entity.
Case Report (n=3)
Provides early clinical experience demonstrating that COVID-19-related multisystem inflammatory syndrome in children can cause severe cardiac complications including myocarditis and cardiogenic shock.
Cardiac involvement as a complication of severe acute respiratory syndrome coronavirus 2 infection in children is a relatively new entity. We present our initial experience managing children with coronavirus disease 2019-related acute myocardial injury. The 3 patients presented here represent a spectrum of the cardiac involvement noted in children with coronavirus disease 2019-related multisystem inflammatory syndrome, including myocarditis presenting as cardiogenic shock or heart failure with biventricular dysfunction, valvulitis, coronary artery changes, and pericardial effusion.
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Jain et al. (2020) conducted a case report in Coronavirus disease 2019-related multisystem inflammatory syndrome with myocarditis (n=3). Coronavirus disease 2019-related multisystem inflammatory syndrome was evaluated on Spectrum of cardiac involvement. Three children with COVID-19-related multisystem inflammatory syndrome presented with a spectrum of cardiac involvement, including myocarditis, cardiogenic shock, heart failure, and coronary changes.
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