Key result
Postoperative renal replacement therapy after open surgical repair of ruptured abdominal aortic aneurysm was associated with significantly higher in-hospital mortality (87% vs 25%, P<0.0001).
Why the study?
Does postoperative renal replacement therapy affect survival in patients who underwent open surgical repair for ruptured abdominal aortic aneurysm?
Cohort (n=94)
Does postoperative renal replacement therapy affect survival in patients who underwent open surgical repair for ruptured abdominal aortic aneurysm?
Absolute Event Rate: 87% vs 25%
p-value: p=<.0001
Postoperative renal replacement therapy following open surgical repair of ruptured abdominal aortic aneurysm is an independent risk factor for mortality.
Signals dismal prognosis after rAAA repair; leaves open whether renal protection strategies improve survival.
OBJECTIVE: To determine the relationship between postoperative renal replacement therapy (RRT) and patient survival after open surgical repair (OR) of ruptured abdominal aortic aneurysm (rAAA). METHODS: A retrospective review of consecutive patients who underwent OR for rAAA repair between January 2002 and July 2008 was performed. Early (<30 days) and late (>30 days) outcomes were assessed. RESULTS: A total of 94 patients (69 men; median [range] age 73.8 [56-89] years) underwent OR of rAAA (infrarenal = 78, juxtarenal = 15, and suprarenal = 1). In-hospital mortality rate was 40% and mean (range) length of intensive care unit (ICU) stay was 9.3 (0-56) days. A total of 23 (24%) patients required postoperative RRT. In-hospital mortality rate was significantly higher (RRT: 87% (20 of 23) vs no RRT: 18 of 71 (25%), P < .0001) and ICU stay significantly longer (RRT: mean (range) days; 14.8 (1-44) vs no RRT: 7.5 (0-56), P = .04) in the RRT patients. On multivariate analysis, RRT (P = .0053) and/or inotropic support (P = .0033) were independent risk factors for death within 30 days of the index procedure. CONCLUSIONS: Renal replacement therapy following OR of rAAA is an independent risk factor for mortality.
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Davies et al. (2010) conducted a cohort in Ruptured abdominal aortic aneurysm (rAAA) (n=94). Postoperative renal replacement therapy (RRT) vs. No RRT was evaluated on In-hospital mortality (p=<.0001). Postoperative renal replacement therapy after open surgical repair of ruptured abdominal aortic aneurysm was associated with significantly higher in-hospital mortality (87% vs 25%, P<0.0001).
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