Key result
A new assay for human interferon measuring the reduction in HA yield of a single-cycle infection with EMC virus showed sensitivity and precision comparable to or better than other assays.
Population
Human lines, diploid cell strains, monkey, rabbit, cat, mouse, pig, cow, dog, and hamster-mouse hybrid cells
Comparison
Encephalomyocarditis virus hemagglutinin yield… vs Other interferon assays
Design
Preclinical
Authors
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May enable broader interferon research across species; leaves open clinical validation before diagnostic adoption.
A new, highly sensitive and simple assay for human interferon was developed using EMC virus hemagglutinin yield reduction, applicable across multiple species.
Jameson et al. (1977) studied this question. Encephalomyocarditis Virus Hemagglutinin Yield Reduction assay vs. other assays tested was evaluated on Sensitivity and precision of the assay. A new assay for human interferon measuring the reduction in HA yield of a single-cycle infection with EMC virus showed sensitivity and precision comparable to or better than other assays.
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