Key result
A 33-year-old man developed an atypical presentation of hand-foot-mouth disease with macular palmoplantar rash and oral ulcers that resolved after 15 days of symptomatic treatment.
Why the study?
Hand-foot-mouth disease is rare in adults and usually presents with atypical symptoms, but its incidence has been increasing.
Case Report (n=1)
Highlights the rare but increasing occurrence of hand-foot-mouth disease in adults, which often presents with atypical symptoms.
Atypical adult HFMD warrants consideration in palmoplantar rashes; this case extends the phenotypic spectrum but leaves broader applicability open.
Hand-foot-mouth syndrome is a common childhood illness. Although occurrence in adults is rare, its incidence has been increasing. In such cases, it usually presents with atypical symptoms. The authors present the case of a 33-year-old male patient who presented with constitutional symptoms, feverish sensation, and macular palmoplantar rash associated with oral and oropharynx ulcers. The epidemiological history revealed exposure to two cohabitants (children) with a recent diagnosis of hand-foot-mouth disease (HFMD).
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Gomes et al. (2023) conducted a case report in Hand-foot-mouth disease (n=1). Symptomatic treatment (sucralfate, paracetamol, hydration) was evaluated. A 33-year-old man developed an atypical presentation of hand-foot-mouth disease with macular palmoplantar rash and oral ulcers that resolved after 15 days of symptomatic treatment.
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