Key result
Three cases of hand, foot, and mouth disease were described in otherwise healthy adults, all of whom experienced complete recovery.
Case Report (n=3)
Highlights that HFMD can present atypically in otherwise healthy adults, though it typically has a benign course with complete recovery.
Supports HFMD consideration in adult vesicular lesion differentials; leaves open need for epidemiologic data beyond case reports.
Hand, foot, and mouth disease (HFMD) is a highly contagious enterovirus infection mainly affecting children less than 5 years of age. In a majority of cases, it is caused by coxsackievirus A16 (CVA16), although instances have been described in which A5, A6, A7, A9, A10, B2, B5, or human enterovirus 71 (HEV-71) has been isolated. The disease occurs rarely in adults, and has been reported in immunocompromised patients. It usually has a benign and self-limiting course with an incubation period of 3-10 days. The prodromal symptoms include fever, malaise, and sore throat. This initial phase is usually followed by erythematous macules, papules, and vesicles on palm and soles, lateral and dorsal surfaces of hands and feet, and also the oral cavity. The purpose of this article is to highlight to the general practitioner about the atypical presentation in healthy adults as well. In the present paper, we describe three cases of HFMD in otherwise healthy adults, with complete recovery.
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Thomas et al. (2015) conducted a case report in Hand, foot, and mouth disease (HFMD) (n=3). Hand, foot, and mouth disease was evaluated on Complete recovery. Three cases of hand, foot, and mouth disease were described in otherwise healthy adults, all of whom experienced complete recovery.
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