Key result
Lymphomatous involvement of the heart can manifest as sick sinus syndrome and seroconstrictive pericarditis due to infiltration of the sinus node by malignant lymphoma cells.
Case Report (n=1)
This case report highlights malignant lymphoma involving the heart as a rare cause of sick sinus syndrome and seroconstrictive pericarditis, confirmed by autopsy.
May prompt lymphoma consideration in unexplained sick sinus syndrome; leaves open need for larger studies before diagnostic change.
A case of the sick sinus syndrome and constrictive pericarditis with effusion (seroconstrictive pericarditis) as manifestations of lymphomatous involvement of the heart is presented. Autopsy findings documented infiltration of the sinus node by undifferentiated malignant lymphoma cells. The clinical course is described and problems with diagnosis and management of such a complication are discussed. This is one of the few cases in the literature in which an uncommon cause of conduction system disease and pericardial constriction was substantiated by electrocardiogram, angiography, and autopsy.
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Donnelly et al. (1981) conducted a case report in Sick sinus syndrome and seroconstrictive pericarditis in malignant lymphoma (n=1). Malignant lymphoma involving the heart was evaluated on Autopsy findings of infiltration of the sinus node by malignant lymphoma cells. Lymphomatous involvement of the heart can manifest as sick sinus syndrome and seroconstrictive pericarditis due to infiltration of the sinus node by malignant lymphoma cells.
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