Key result
Leadless pacemaker implantation and chemotherapy successfully treated an 85-year-old man with secondary cardiac lymphoma presenting as sick sinus syndrome and atrial fibrillation.
Why the study?
Cardiac involvement of malignant lymphoma is relatively common, although it has subclinical manifestations that are difficult to detect.
Case Report (n=1)
Leadless pacemaker implantation is a safe and feasible option for patients with sick sinus syndrome secondary to cardiac lymphoma causing partial SVC obstruction.
Supports leadless pacemaker in rare cardiac lymphoma; leaves open generalizability without prospective data.
Cardiac involvement of malignant lymphoma is relatively common, although such a phenomenon has subclinical manifestations that are difficult to detect. We herein describe a patient with atrial fibrillation and sick sinus syndrome as the main symptoms. Computed tomography showed a mass in the right atrium extending into the superior vena cava (SVC). We implanted the patient with a leadless pacemaker. Transvenous biopsy revealed a diffuse large B-cell lymphoma. The patient was treated successfully with chemotherapy including rituximab. This case suggested that cardiac lymphoma may cause sick sinus syndrome, and leadless pacemaker implantation is a safe treatment option in patients with partial SVC obstruction.
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Kondo et al. (2020) conducted a case report in Secondary cardiac lymphoma presenting as sick sinus syndrome and atrial fibrillation (n=1). Leadless pacemaker implantation and chemotherapy was evaluated on Resolution of symptoms and tumor reduction. Leadless pacemaker implantation and chemotherapy successfully treated an 85-year-old man with secondary cardiac lymphoma presenting as sick sinus syndrome and atrial fibrillation.
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