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January 1, 2005Korean Journal of AnesthesiologyOpen Access

Hemodynamic and Preemptive Analgesic Effect of Preoperative Epidural Analgesia during Laparoscopic Hysterectomy

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Key result

Preemptive epidural analgesia produced a more stable hemodynamic state during laparoscopic hysterectomy and significantly reduced postoperative pain compared to control.

Why the study?

Does preemptive epidural analgesia improve intraoperative hemodynamics and reduce postoperative pain in ASA 1 and 2 patients undergoing laparoscopic hysterectomy?

Population

50 ASA 1 and 2 patients undergoing laparoscopic hysterectomy

Comparison

Preemptive epidural analgesia before induction… vs Control group

Design

RCT, randomized to two groups

Follow-up

24 hours postoperatively

Authors

JPJung Wook ParkDuke UniversityYKYoung Soon KimNational Institute of Agricultural Science and TechnologyJOJong In OhChung-Ang University

Discussion

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Implication

Supports preemptive epidural analgesia in laparoscopic hysterectomy; extends RCT evidence to gynecologic laparoscopy.

Study Design

Type

RCT (n=50)

Structured PICO

Does preemptive epidural analgesia improve intraoperative hemodynamics and reduce postoperative pain in ASA 1 and 2 patients undergoing laparoscopic hysterectomy?

P
Population
50 ASA 1 and 2 patients undergoing laparoscopic hysterectomy.
I
Intervention
Preemptive epidural analgesia (1% lidocaine 10 ml injected via epidural catheter) before induction of general anesthesia
C
Comparator
Control group (nothing applied before inducing general anesthesia)
O
Outcome
Intraoperative hemodynamics (blood pressures, heart rates, cardiac outputs, stroke volumes, and cardiac indexes) and postoperative pain scores (100 mm visual analogue scale at 1, 3, 6, 12 and 24 hours postoperatively)surrogate

Preemptive epidural analgesia with lidocaine provides better hemodynamic stability and postoperative pain control during laparoscopic hysterectomy.

Cite This Study

Park et al. (2005) conducted an RCT in Laparoscopic hysterectomy (n=50). Preemptive epidural analgesia vs. No epidural analgesia (control) was evaluated on Intraoperative hemodynamics and postoperative pain scores. Preemptive epidural analgesia produced a more stable hemodynamic state during laparoscopic hysterectomy and significantly reduced postoperative pain compared to control.

synapsesocial.com/papers/6a93a1241eecaf8548720f78https://doi.org/10.4097/kjae.2005.49.5.630
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Epidural Anesthesia and Analgesia in High-risk Surgical Patients1987 · 993 citations
  2. 2The Combination of General Anaesthesia and Epidural Block I: The Effects of Sequence of Induction on Haemodynamic Variables and Blood Gas Measurements in Healthy Patients1979 · 16 citations
  3. 3Combined Epidural and General Anesthesia versus General Anesthesia for Abdominal Aortic Surgery1991 · 234 citations
  4. 4Can pre‐emptive lumbar epidural blockade reduce postoperative pain following lower abdominal surgery?1993 · 78 citations