Why the study?
Does early administration of intravenous immunoglobulin reduce the incidence of coronary artery lesions in patients with Kawasaki disease?
Population
229 patients with confirmed Kawasaki disease in Finland, mean age 3.9 years, male/female ratio 1.5:1.
Comparison
Intravenous immunoglobulin administered at… vs Comparison between different timings of IVIG…
Design
Cohort
Authors
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Early IVIG may reduce coronary lesions in Kawasaki disease; hypothesis-generating pending randomized confirmation.
Does early administration of intravenous immunoglobulin reduce the incidence of coronary artery lesions in patients with Kawasaki disease?
Early administration of intravenous immunoglobulin (before day 7) in Kawasaki disease is associated with a lower incidence of coronary artery lesions compared to later administration.
Eeva Salo (1993) studied this question.
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