Key result
The incidence of recurrent Kawasaki disease in Japan was 3.89 per 1000 person-years between 2003 and 2012, remaining largely unchanged over the past 30 years.
Population
81,310 patients with Kawasaki disease in Japan from nationwide surveys (2003-2012)
Design
Cohort
Follow-up
2003-2012
Authors
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Stable recurrent KD rates over 30 years warrant no change in surveillance; leaves open targeted prevention trials in high-risk subgroups.
Observational (n=81,310)
Yes
The incidence of recurrent Kawasaki disease in Japan has remained stable over 30 years, with male sex, age under three, and initial resistance to immunoglobulin therapy identified as key risk factors.
Sudo et al. (2017) conducted an observational in Kawasaki disease (n=81,310). Risk factors for recurrence (male sex, age <3 years, IVIG/steroid therapy) vs. Females, older age, no IVIG/steroid therapy was evaluated on Incidence rate of recurrent Kawasaki disease. The incidence of recurrent Kawasaki disease in Japan was 3.89 per 1000 person-years between 2003 and 2012, remaining largely unchanged over the past 30 years.
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