Key result
Indexed LVESD, LAESD, and minimum MAA on 3.0T MRI distinguished no/mild from moderate/severe mitral regurgitation in DCM patients (AUCs 0.876, 0.816, and 0.773, respectively; all P<0.05).
Why the study?
Can 3.0T cardiac MRI morphological and functional parameters predict the severity of mitral regurgitation in patients with dilated cardiomyopathy?
Population
41 patients with dilated cardiomyopathy (DCM) and 26 healthy control subjects
Comparison
3.0 T cardiac magnetic resonance imaging and… vs Healthy control subjects
Design
Cross-sectional
Authors
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MRI correlations with MR severity in DCM are hypothesis-generating; prospective validation needed before clinical adoption.
Cross-Sectional (n=67)
Can 3.0T cardiac MRI morphological and functional parameters predict the severity of mitral regurgitation in patients with dilated cardiomyopathy?
Effect estimate: AUC 0.876, 0.816, and 0.773
p-value: p=< 0.05
Indexed LVESD, LAESD, and minimum MAA measured by 3.0T cardiac MRI can accurately predict the severity of mitral regurgitation in patients with dilated cardiomyopathy.
Wen et al. (2016) conducted a cross-sectional in Dilated cardiomyopathy (n=67). 3.0T cardiac MRI parameters (indexed LVESD, LAESD, minimum MAA) vs. Healthy controls and patients with no/mild mitral regurgitation was evaluated on Distinguishing no/mild from moderate/severe mitral regurgitation (AUC 0.876, 0.816, and 0.773, p=< 0.05). Indexed LVESD, LAESD, and minimum MAA on 3.0T MRI distinguished no/mild from moderate/severe mitral regurgitation in DCM patients (AUCs 0.876, 0.816, and 0.773, respectively; all P<0.05).
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