Key result
In healthy male smokers, smoking the first cigarette of the day significantly decreased blood pressure variability in the Mayer wave frequency range from 7.1 to 3.2 mmHg2 (P<0.01).
Why the study?
Does smoking a cigarette affect short-term blood pressure variability and haemodynamic parameters in healthy male smokers compared to non-smokers?
Population
40 healthy male volunteers (20 smokers and 20 non-smokers)
Comparison
Smoking 4 cm of a cigarette containing 1 mg of… vs Control group of non-smokers who were not asked…
Design
Cohort, open study
Follow-up
over a single day (morning and afternoon)
Authors
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Smoking the first cigarette was associated with reduced morning BP variability in male smokers; hypothesis-generating for sympathetic effects, needs confirmation before clinical relevance.
Does smoking a cigarette affect short-term blood pressure variability and haemodynamic parameters in healthy male smokers compared to non-smokers?
p-value: p=< 0.01
Overnight smoking cessation in smokers is associated with increased sympathetic activity in the morning, which is released by smoking the first cigarette, an effect that is blunted after continuous smoking throughout the day.
Ragueneau et al. (1999) studied Healthy (n=40). Cigarette smoking vs. Non-smokers not asked to smoke was evaluated on Blood pressure variability in the frequency range of the Mayer waves (66-129 mHz) (p=< 0.01). In healthy male smokers, smoking the first cigarette of the day significantly decreased blood pressure variability in the Mayer wave frequency range from 7.1 to 3.2 mmHg2 (P<0.01).
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