Key result
Percutaneous transvenous mitral commissurotomy achieved a minimum one-third reduction in pulmonary artery systolic pressure in 96% of patients with severe mitral stenosis.
Why the study?
The study was conducted to assess the reduction in severe pulmonary hypertension after PTMC in patients with severe mitral stenosis.
Does PTMC reduce pulmonary artery systolic pressure in patients with severe mitral stenosis and severe pulmonary hypertension?
Cross-Sectional (n=124)
No
Does PTMC reduce pulmonary artery systolic pressure in patients with severe mitral stenosis and severe pulmonary hypertension?
Answers are grounded in this paper and cite their sources.
PTMC is highly effective at immediately reducing severe pulmonary hypertension in patients with severe mitral stenosis.
Objective: The objective of our study was to assess the reduction in severe pulmonary hypertension after PTMC in patients of severe mitral stenosis. Methodology: One hundred twenty-four patients of severe mitral stenosis with severely elevated pulmonary pressures more than 50 mmHg between 15 to 60 years of age of either gender undergoing elective PTMC at Chaudry Pervaiz Elahi Institute of Cardiology, Multan were included in this study. Post PTMC pulmonary pressures were noted 24 hours after PTMC. Results: Mean age of the patients was 35.45 ± 10.38 years. Diabetes mellitus was found to be present in 39/124 (31.5%), hypertension in 40/124 (32.3%) while no comorbidities were found in 62/124 (50%). Mean baseline pulmonary artery systolic pressure was found to be 72.61 ± 8.11 mmHg while mean pulmonary artery systolic pressure after PTMC was found to be 45.09 ± 6.06 mmHg. The pulmonary artery systolic pressure fallen from baseline by 37.92 ± 4.19 mmHg after the commissurotomy. Transvenous mitral commissurotomy was found to be effective with a minimum 1/3rd reduction in 119/124 (96%) while it was ineffective in 5/124 (4%) of the patients. Conclusion: Therefore, we conclude that balloon valvotomy is a useful procedure which results in a significant reduction in mean pulmonary artery systolic pressure irrespective of age, gender or comorbidities.
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Ali et al. (2021) conducted a cross-sectional in Severe mitral stenosis with severe pulmonary hypertension (n=124). Percutaneous transvenous mitral commissurotomy (PTMC) vs. Baseline (pre-PTMC) was evaluated on Reduction in pulmonary artery systolic pressure by at least one-third from baseline. Percutaneous transvenous mitral commissurotomy achieved a minimum one-third reduction in pulmonary artery systolic pressure in 96% of patients with severe mitral stenosis.
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