Key result
The presence of ascites independently predicted left ventricular diastolic dysfunction in patients with liver cirrhosis (OR 4.19), along with higher MELD score and lower serum albumin.
Why the study?
Left ventricular diastolic dysfunction increases morbidity and mortality in cirrhosis, but studies evaluating its predictive factors in India are sparse.
What are the independent clinical predictors of left ventricular diastolic dysfunction in patients with liver cirrhosis?
Population
104 patients with cirrhosis
Design
Prospective study
Authors
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Low albumin, high MELD, and ascites predict LVDD in cirrhosis; leaves open whether targeted screening improves outcomes.
Cross-Sectional (n=104)
No
What are the independent clinical predictors of left ventricular diastolic dysfunction in patients with liver cirrhosis?
Odds Ratio: 4.19 (95% CI 1.38–12.65)
p-value: p=<0.01
Low serum albumin, high MELD score, and the presence of ascites are independent predictors of left ventricular diastolic dysfunction in patients with liver cirrhosis.
Behera et al. (2021) conducted a cross-sectional in Liver Cirrhosis (n=104). Presence of ascites vs. Absence of ascites was evaluated on Left ventricular diastolic dysfunction (LVDD) (OR 4.19, 95% CI 1.38-12.65, p=<0.01). The presence of ascites independently predicted left ventricular diastolic dysfunction in patients with liver cirrhosis (OR 4.19), along with higher MELD score and lower serum albumin.
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