Key result
Left ventricular diastolic dysfunction was present in 49.7% of cirrhosis patients, with age >55 years (OR 3.895) and QTc >440 ms (OR 2.382) identified as significant independent predictors.
Why the study?
Cirrhosis patients with left ventricular diastolic dysfunction (LVDD) have a poor prognosis, but little is known about these individuals.
Population
398 consecutive cirrhosis patients at a single hospital in China
Comparison
LVDD group vs normal left ventricular diastolic function group
Design
Single-center retrospective cross-sectional study
Authors
Loading...
LVDD screening may be warranted in cirrhosis patients with these factors; leaves open whether intervention improves outcomes.
Cross-Sectional (n=398)
No
Odds Ratio: 3.895 (95% CI 2.424–6.258)
p-value: p=<0.001
Left ventricular diastolic dysfunction is highly prevalent in patients with cirrhosis and is independently associated with older age, higher BMI, decompensated liver function, and prolonged QTc interval.
Hu et al. (2021) conducted a cross-sectional in Liver Cirrhosis (n=398). Age >55 years vs. Age ≤55 years was evaluated on Left ventricular diastolic dysfunction (LVDD) (OR 3.895, 95% CI 2.424-6.258, p=<0.001). Left ventricular diastolic dysfunction was present in 49.7% of cirrhosis patients, with age >55 years (OR 3.895) and QTc >440 ms (OR 2.382) identified as significant independent predictors.