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November 19, 2025Romanian Journal of Internal MedicineOpen Access

Left Ventricular Diastolic Dysfunction Increases the Risk of Medium-term Mortality in Patients with Cirrhotic Ascites

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Authors

SLSheng Hao LiLZLu ZhangHLHong Juan Li

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Overview

Retrospective analysis shows left ventricular diastolic dysfunction is an independent risk factor for 1-year mortality in patients with cirrhotic ascites, suggesting clinical significance.

Key Points

  • To determine the influence of left ventricular diastolic dysfunction on medium-term mortality in cirrhotic ascites patients.
  • Retrospective study of 194 patients with cirrhotic ascites
  • Patients categorized into LVDD and non-LVDD groups based on echocardiography
  • Utilized Lasso and Cox regression analyses to identify risk factors
  • Assessed predictive value using Kaplan–Meier and ROC curves
  • 47.4% of patients exhibited left ventricular diastolic dysfunction
  • Cox regression identified LVDD as an independent risk factor with a hazard ratio of 2.109 (P = 0.003)
  • Predictive performance of LVDD for mortality comparable to CTP and MELD scores

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/6924f095c0ce034ddc350c64https://doi.org/10.2478/rjim-2025-0022
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Left Ventricular Diastolic Dysfunction Increases the Risk of Medium-term Mortality in Patients with Cirrhotic Ascites2025
  2. 2A case-cohort study of left ventricular diastolic dysfunction in patients with cirrhosis: the liver–heart axis2023 · 4 citations
  3. 3Cardiac diastolic dysfunction predicts poor prognosis in patients with decompensated liver cirrhosis2018 · 36 citations
  4. 4Diastolic dysfunction is a predictor of poor outcomes in patients with cirrhosis, portal hypertension, and a normal creatinine2013 · 180 citations
  5. 5Association of left ventricular diastolic dysfunction with inflammatory activity, renal dysfunction, and liver-related mortality in patients with cirrhosis and ascites2024 · 4 citations