Why the study?
The impact of left ventricular diastolic dysfunction on survival after liver transplant was not known, especially when defined using current diagnostic criteria.
Does left ventricular diastolic dysfunction (LVDD) per 2016 ASE criteria increase all-cause mortality after a liver transplant in patients with end-stage liver disease?
Population
Cirrhotic patients undergoing liver transplant across screened cohort studies
Comparison
Presence vs absence of LVDD per 2016 American Society of Echocardiography criteria
Design
Systematic review and meta-analysis of cohort studies
Key result
Left ventricular diastolic dysfunction defined by 2016 ASE criteria showed no significant difference in mortality after liver transplant in a meta-analysis of two studies.
Authors
Loading...
Pretransplant LVDD by 2016 ASE criteria shows no post-LT mortality difference; leaves open whether older criteria or other CCM features predict outcomes.
Systematic Review
Does left ventricular diastolic dysfunction (LVDD) per 2016 ASE criteria increase all-cause mortality after a liver transplant in patients with end-stage liver disease?
Current evidence is insufficient to definitively link LVDD defined by 2016 ASE criteria to increased mortality after liver transplantation, highlighting the need for prospective studies.
González-Martínez et al. (2023) conducted a systematic review in End-stage liver disease. Left ventricular diastolic dysfunction (LVDD) vs. Without LVDD was evaluated on All-cause mortality after a liver transplant. Left ventricular diastolic dysfunction defined by 2016 ASE criteria showed no significant difference in mortality after liver transplant in a meta-analysis of two studies.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: