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January 6, 2023Frontiers in SurgeryOpen Access

The predictive value of revised diastolic dysfunction in outcomes of liver transplantation: A propensity score matching analysis

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Why the study?

Research regarding the effects of revised diastolic dysfunction on post-liver transplantation outcomes remains limited.

Does the presence of diastolic dysfunction predict cardiovascular adverse events and mortality in patients undergoing liver transplantation for decompensated cirrhosis?

Population

231 patients undergoing liver transplantation for decompensated cirrhosis

Comparison

Diastolic dysfunction vs non-diastolic dysfunction

Design

Retrospective propensity score-matched study

Follow-up

At least 1 year post-LT

Authors

SBShenghua BiYJYueping JiangWZWenjun Zhao

Discussion

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Member takes

Overview

Revised DD was associated with higher post-LT mortality and AEs; leaves open whether it should guide pre-LT risk stratification.

Structured PICO

Does the presence of diastolic dysfunction predict cardiovascular adverse events and mortality in patients undergoing liver transplantation for decompensated cirrhosis?

P
Population
231 patients who underwent liver transplantation (LT) for decompensated cirrhosis. The diastolic dysfunction (DD) group (n=153) had a mean age of 51.5 ± 9.5 years and was 81.8% male.
I
Intervention
Presence of diastolic dysfunction (DD) based on revised 2019 cirrhotic cardiomyopathy criteria
C
Comparator
Absence of diastolic dysfunction (non-DD group), analyzed using 1:2 propensity score matching
O
Outcome
Cardiovascular adverse events and survival status at least 1 year post-liver transplantationhard clinical

Diastolic dysfunction is a significant predictor of perioperative cardiovascular adverse events and 1-year mortality in patients undergoing liver transplantation for decompensated cirrhosis.

Cite This Study

Bi et al. (2023) studied this question.

synapsesocial.com/papers/6a910e875d48fdaeb8caf3fbhttps://doi.org/10.3389/fsurg.2022.1072908
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diastolic dysfunction: Prevalence and outcome in liver transplantation candidates2025 · 4 citations
  2. 2Impact of left ventricular diastolic dysfunction on liver transplantation outcomes based on the latest American Society of Echocardiography/European Association of Cardiovascular Imaging recommendations2021 · 12 citations
  3. 3Left Ventricular Diastolic Dysfunction Defined Using the 2016 ASE Criteria and Mortality after a Liver Transplant in Patients with End-Stage Liver Disease: A Systematic Review2023
  4. 4Prevalence and outcome of diastolic dysfunction in liver transplantation recipients2014 · 47 citations
  5. 5Cardiac diastolic dysfunction predicts poor prognosis in patients with decompensated liver cirrhosis2018 · 36 citations