Key result
Diastolic dysfunction was present in 43% of liver transplant recipients but did not significantly affect outcomes, whereas moderate/severe tricuspid regurgitation predicted worse survival (P=0.01).
Why the study?
Does the presence of diastolic dysfunction or tricuspid regurgitation affect post-transplantation mortality and cardiovascular complications in liver transplantation recipients?
Population
173 liver transplantation (LTx) recipients
Comparison
Presence of diastolic dysfunction or… vs Absence of diastolic dysfunction or no/mild…
Design
Cohort
Authors
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TR assessment may refine pre-liver transplant risk stratification; Level 3 evidence leaves open validation and intervention trials.
Cohort (n=173)
Does the presence of diastolic dysfunction or tricuspid regurgitation affect post-transplantation mortality and cardiovascular complications in liver transplantation recipients?
In liver transplant recipients, moderate/severe tricuspid regurgitation, but not diastolic dysfunction, is predictive of worse post-transplantation survival.
Raevens et al. (2014) conducted a cohort in Cirrhotic cardiomyopathy in liver transplantation candidates (n=173). Diastolic dysfunction vs. No diastolic dysfunction was evaluated on Mortality and cardiovascular complications post-transplantation. Diastolic dysfunction was present in 43% of liver transplant recipients but did not significantly affect outcomes, whereas moderate/severe tricuspid regurgitation predicted worse survival (P=0.01).
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