Key result
Left ventricular diastolic dysfunction linked to ~111% higher 1-year mortality risk in cirrhotic ascites.
Why the study?
The study was conducted to elucidate the impact of left ventricular diastolic dysfunction on the risk of medium-term poor prognosis in patients with cirrhotic ascites.
Does left ventricular diastolic dysfunction increase the risk of 1-year mortality in patients with cirrhotic ascites?
Population
194 patients with cirrhotic ascites
Comparison
LVDD vs non-LVDD based on echocardiography
Design
Retrospective study
Follow-up
1-year
Authors
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May inform prognosis in cirrhotic ascites; hypothesis-generating before integration into risk models.
Cohort (n=194)
No
Does left ventricular diastolic dysfunction increase the risk of 1-year mortality in patients with cirrhotic ascites?
Effect estimate: HR 2.109 (95% CI 1.279-3.478)
p-value: p=0.003
Left ventricular diastolic dysfunction is an independent predictor of 1-year mortality in patients with cirrhotic ascites, performing comparably to traditional CTP and MELD scores.
Li et al. (2025) conducted a cohort in Cirrhotic ascites (n=194). Left ventricular diastolic dysfunction (LVDD) vs. Non-LVDD was evaluated on 1-year mortality (HR 2.109, 95% CI 1.279-3.478, p=0.003). Left ventricular diastolic dysfunction independently increased the risk of 1-year mortality (HR 2.109) compared to normal diastolic function in patients with cirrhotic ascites.
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