Key result
Routine screening and revascularization in asymptomatic patients with suspected coronary artery disease do not improve survival or reduce myocardial infarction rates compared to medical therapy.
Why the study?
Does myocardial revascularization reduce mortality compared to guideline-directed medical therapy in asymptomatic patients with suspected coronary artery disease?
Does myocardial revascularization reduce mortality compared to guideline-directed medical therapy in asymptomatic patients with suspected coronary artery disease?
Answers are grounded in this paper and cite their sources.
The article highlights the discrepancy between robust RCT evidence showing no mortality benefit of revascularization over GDMT in chronic coronary syndromes and the frequent real-world use of PCI in asymptomatic patients.
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Rocha et al. (2026) conducted an editorial in Coronary Artery Disease. Routine screening and revascularization vs. Guideline-directed medical therapy was evaluated. Routine screening and revascularization in asymptomatic patients with suspected coronary artery disease do not improve survival or reduce myocardial infarction rates compared to medical therapy.
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