Key result
A novel cardiac assist valve with a purge flow effectively increased fluid exchange and washout in the valve sinuses compared with a standard valve in experimental and computational models.
Population
In vitro and computational fluid dynamics models of a cardiac assist valve
Comparison
Novel cardiac assist valve design with a purge… vs Valve without a purge flow
Design
Preclinical
Authors
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May reduce sinus thrombosis risk in assist devices; hypothesis-generating and requires human trials before practice change.
A novel cardiac assist valve design with purge flow improves fluid exchange in the sinuses in vitro, potentially reducing the risk of thrombus formation in stagnation zones.
Affeld et al. (1998) studied Thromboembolic complications in cardiac assist systems. Novel cardiac assist valve with a purge flow vs. Valve without a purge flow was evaluated on Fluid exchange and washout in the valve sinuses. A novel cardiac assist valve with a purge flow effectively increased fluid exchange and washout in the valve sinuses compared with a standard valve in experimental and computational models.
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