Key result
A novel cardiac assist valve with a sinus purge flow minimizes stagnation areas in the sinus and may avoid thrombus formation.
Population
32 models of a monoleaflet valve for cardiac assist systems
Design
Preclinical
Authors
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Supports development of purge-flow valves to reduce thrombosis risk; leaves open translation from animal models to clinical use.
A novel cardiac assist valve design with a purge flow reduces stagnation areas in vitro, which may help prevent thromboembolic complications.
Timmel et al. (2001) studied Thromboembolic complications in cardiac assist systems (n=32). Novel cardiac assist valve with a purge flow was evaluated on Washout of a dye filled in the sinus (stagnation areas). A novel cardiac assist valve with a sinus purge flow minimizes stagnation areas in the sinus and may avoid thrombus formation.
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