Key result
Cardiac tamponade decreased total left circumflex coronary blood flow by 51% and caused the systolic portion of this flow to become negative or retrograde in awake dogs.
Why the study?
Does cardiac tamponade affect coronary hemodynamics in awake dogs?
Population
Six awake dogs
Comparison
Cardiac tamponade at several degrees vs Control period (baseline)
Design
Preclinical
Authors
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Supports ischemia contributing to tamponade dysfunction in dogs; leaves open translation to human coronary hemodynamics.
Does cardiac tamponade affect coronary hemodynamics in awake dogs?
Effect estimate: 51% decrease
Cardiac tamponade significantly decreases coronary blood flow, particularly during systole, suggesting myocardial ischemia may contribute to depressed cardiac function in this condition.
Jarmakani et al. (1975) studied Cardiac tamponade (n=6). Cardiac tamponade vs. Control period was evaluated on Total left circumflex coronary blood flow (51% decrease). Cardiac tamponade decreased total left circumflex coronary blood flow by 51% and caused the systolic portion of this flow to become negative or retrograde in awake dogs.
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