Key result
The CorAide blood pump implanted in 18 calves for 1 to 3 months demonstrated stable hemodynamics (mean flow 5.9 L/min) with no bleeding, organ dysfunction, or mechanical failure.
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Stable calf performance supports device refinement; leaves open human safety and efficacy.
Fukamachi et al. (2002) studied this question. Cleveland Clinic CorAide left ventricular assist system was evaluated on Chronic in vivo system performance and biocompatibility. The CorAide blood pump implanted in 18 calves for 1 to 3 months demonstrated stable hemodynamics (mean flow 5.9 L/min) with no bleeding, organ dysfunction, or mechanical failure.
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