Key result
The TRISKELION 3D-printed heart valve prototype had a regurgitation fraction of 22.26%, compared to 8.55% for a biological valve and 13.23% for a mechanical valve in a pulse duplicator setup.
Why the study?
Developing a prosthetic heart valve combining the hemodynamic properties of biological valves with the longevity of mechanical prostheses remains a major challenge.
Population
3D-printed silicone heart valve prototypes tested in a hemodynamic pulse duplicator
Comparison
TRISKELION prototype vs standard bioprosthesis vs mechanical bileaflet valve
Design
In vitro experimental bioengineering study
Authors
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Supports 3D-printed valve prototyping; leaves open in vivo durability and efficacy testing before clinical consideration.
The TRISKELION 3D-printed polymeric heart valve prototype demonstrates feasible hemodynamic properties in an in vitro setup, providing a proof-of-concept for rapid prototyping of anatomically inspired artificial valves.
Tschorn et al. (2022) studied Prosthetic heart valve development. TRISKELION 3D printed polymeric heart valve prototype vs. Standard bioprosthesis and mechanical valve was evaluated on Regurgitation fraction. The TRISKELION 3D-printed heart valve prototype had a regurgitation fraction of 22.26%, compared to 8.55% for a biological valve and 13.23% for a mechanical valve in a pulse duplicator setup.
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