Key result
In vitro testing of the ReinHeart TAH 2.0 demonstrated that a positive flow balance is achieved over the full range of tested afterloads, with a maximum flow difference of 0.7 L/min at high atrial pressures.
Why the study?
The study was conducted to identify the preload and afterload sensitivity of the ReinHeart TAH 2.0 and evaluate flow balance controllability using a reduced right stroke volume and active diastolic adaptation.
Population
ReinHeart TAH 2.0 tested in an active mock circulation loop
Comparison
Various preload and afterload conditions across four scenarios
Design
In vitro simulation study
Authors
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Mock-loop data on ReinHeart TAH 2.0 flow balance are hypothesis-generating; prospective in vivo studies needed before clinical translation.
In vitro testing of the ReinHeart TAH 2.0 demonstrated adequate controllability of flow balance across a wide range of physiological preload and afterload conditions.
Hildebrand et al. (2021) studied this question. ReinHeart TAH 2.0 was evaluated on Preload and afterload sensitivity and flow balance controllability. In vitro testing of the ReinHeart TAH 2.0 demonstrated that a positive flow balance is achieved over the full range of tested afterloads, with a maximum flow difference of 0.7 L/min at high atrial pressures.
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