Why the study?
Does a right stroke volume limiter improve left-right hemodynamic balance in a total artificial heart model?
Population
In vitro models and in vivo models implanted with the Cleveland Clinic-Nimbus total artificial heart
Comparison
Right stroke volume limiter at 10%, 15%, and 20%… vs TAH operation at maximum beat rate without SVL
Design
Preclinical
Follow-up
more than 1 month (for 2 surviving calves)
Authors
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SVL shows promise in animal TAH models; leaves open clinical translation pending human trials.
Does a right stroke volume limiter improve left-right hemodynamic balance in a total artificial heart model?
A right stroke volume limiter of 10% to 15% effectively maintains left-right hemodynamic balance in a total artificial heart model at maximum beat rates.
Fukamachi et al. (1993) studied this question.
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