Key result
A small-diameter interatrial shunt in a totally implantable artificial heart achieved excellent right-left ventricular output balance, maintaining left atrial pressure 5 mmHg above right atrial pressure.
Population
Totally implantable artificial heart model
Comparison
Small-diameter interatrial shunt (IAS) vs Volume-displacement chambers (VDC)
Design
Preclinical
Authors
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May enable simpler totally implantable artificial hearts; leaves open human translation from this animal model.
An interatrial shunt in a totally implantable artificial heart effectively balances right and left atrial pressures, eliminating the need for bulky volume-displacement chambers.
Olsen et al. (1991) studied Right-left ventricular output balance in artificial hearts. Small-diameter interatrial shunt (IAS) vs. Volume-displacement chambers (VDC) was evaluated on Right-left ventricular output balance (net flow and atrial pressures). A small-diameter interatrial shunt in a totally implantable artificial heart achieved excellent right-left ventricular output balance, maintaining left atrial pressure 5 mmHg above right atrial pressure.
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