In pediatric atrial myocardium, alpha1-adrenoceptors may be located closer to adrenergic nerve terminals than beta-adrenoceptors, playing a key role in low-intensity sympathetic inotropic control.
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Alpha1-adrenoceptors may mediate closer endogenous inotropy than beta in atrial tissue; hypothesis-generating for pediatric sympathetic control, requires human confirmation.
Borthne et al. (2000) studied this question.
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