Key result
Administration of protamine in a patient with unrecognized risk factors, including prior exposure and vasectomy, resulted in a type 1 allergic reaction with anaphylaxis.
Population
A patient with risk factors for allergic reaction to protamine, including prior protamine exposure and…
Design
Case_report
Authors
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Preoperative screening for protamine risk factors may avert anaphylaxis; single case leaves open prospective validation of avoidance strategies.
Case Report (n=1)
Screening for risk factors such as prior protamine exposure, vasectomy, shellfish allergy, and insulin-dependent diabetes is crucial before protamine administration to prevent or prepare for potentially fatal anaphylaxis.
Singh et al. (2017) conducted a case report in Protamine anaphylaxis (n=1). Protamine was evaluated on Type 1 allergic reaction with anaphylaxis. Administration of protamine in a patient with unrecognized risk factors, including prior exposure and vasectomy, resulted in a type 1 allergic reaction with anaphylaxis.
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