Key result
Administration of protamine sulfate resulted in a lethal anaphylactic reaction in a non-diabetic patient following uneventful replacement of the ascending aorta.
Case Report (n=1)
Highlights the rare but potentially lethal risk of anaphylactic reaction to protamine sulfate during cardiac surgery, even in non-diabetic patients.
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Clinicians should remain vigilant for protamine anaphylaxis even in non-diabetics; this case report leaves open questions on incidence and prevention.
Anthony L. Panos (2003) conducted a case report in Anaphylactic reaction to protamine (n=1). Protamine sulfate was evaluated on Lethal anaphylactic reaction. Administration of protamine sulfate resulted in a lethal anaphylactic reaction in a non-diabetic patient following uneventful replacement of the ascending aorta.
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