Key result
Treatment with a bronchodilator, steroids, and extracorporeal membrane oxygenation successfully managed a catastrophic bronchial spasm due to severe protamine anaphylaxis.
Severe anaphylactic reaction to protamine presenting as catastrophic bronchial spasm during cardiac surgery can be successfully managed with bronchodilators, steroids, and ECMO.
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Rare protamine anaphylaxis with bronchospasm warrants vigilance in cardiac surgery; leaves open optimal rescue protocols.
Kim et al. (2016) studied this question. Treatment with a bronchodilator, steroids, and extracorporeal membrane oxygenation successfully managed a catastrophic bronchial spasm due to severe protamine anaphylaxis.
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