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January 1, 2015Saudi Journal of Kidney Diseases and TransplantationOpen Access

Solute clearance measurement in the assessment of dialysis adequacy among African continuous ambulatory peritoneal dialysis patients

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Key result

Weekly Kt/V (mean 1.7) was within recommended values for the majority of CAPD patients and showed no significant association with blood pressure, hemoglobin, or other biochemical indices.

Population

70 continuous ambulatory peritoneal dialysis patients at the Charlotte Maxeke Johannesburg Academic…

Design

Cross-sectional

Authors

AAAliyu AbduAminu Kano Teaching HospitalSNSagren NaidooSMShirin Malgas

Discussion

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Overview

Meeting Kt/V targets may not reflect broader adequacy in CAPD; leaves open validation of additional indices in low-resource settings.

Study Design

Type

Cross-Sectional (n=70)

Multicenter

No

Structured PICO

P
Population
70 patients on continuous ambulatory peritoneal dialysis (mean age 37.9 years, 43% female, 86% black African) with a mean duration on CAPD of 19.7 months.
E
Exposure
Solute clearance measurement using urea clearance (Kt/V)
O
Outcome
Solute clearance (weekly Kt/V) and its relationship with other parameters of PD adequacy (blood pressure, hemoglobin, and other biochemical parameters)surrogate

In a predominantly low socioeconomic status African CAPD population, the majority achieved recommended weekly Kt/V doses, though Kt/V was not significantly associated with other indices of dialysis adequacy.

Cite This Study

Abdu et al. (2015) conducted a cross-sectional in Continuous ambulatory peritoneal dialysis (CAPD) (n=70). Weekly Kt/V (solute clearance) was evaluated on Association of weekly Kt/V with blood pressure, hemoglobin, and other biochemical parameters. Weekly Kt/V (mean 1.7) was within recommended values for the majority of CAPD patients and showed no significant association with blood pressure, hemoglobin, or other biochemical indices.

synapsesocial.com/papers/6a93c8a0f92a43743f28b04ehttps://doi.org/10.4103/1319-2442.160228
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1CKD Prevention in Sub-Saharan Africa: A Call for Governmental, Nongovernmental, and Community Support2008 · 177 citations
  2. 2Peritoneal solute transport—we know it is important, but what is it?2000 · 16 citations
  3. 3Increased peritoneal membrane transport is associated with decreased patient and technique survival for continuous peritoneal dialysis patients. The Canada-USA (CANUSA) Peritoneal Dialysis Study Group.1998 · 515 citations