Why the study?
Is urea clearance alone superior to both urea and creatinine clearances as an index of small solute clearance adequacy in peritoneal dialysis?
Population
Patients undergoing peritoneal dialysis (PD)
Comparison
Assessment of PD adequacy using urea clearance vs Assessment using both urea and creatinine…
Design
Review
Authors
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May support urea clearance as sole PD adequacy index; leaves open prospective validation before guideline changes.
Is urea clearance alone superior to both urea and creatinine clearances as an index of small solute clearance adequacy in peritoneal dialysis?
The authors propose that urea clearance is the preferred index of peritoneal dialysis adequacy, challenging the necessity of measuring both creatinine and urea clearances.
Tzamaloukas et al. (2000) studied this question.
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