Key result
A repair-oriented strategy for the aortic valve in children achieved a 95% Kaplan-Meier freedom from reintervention at 3 years among survivors, with significant gradient reductions.
Cohort (n=39)
A repair-oriented strategy for the aortic valve in children provides satisfactory early and mid-term results with significant reductions in gradient and high freedom from reintervention.
Supports consideration of repair-oriented aortic valve strategies in children; leaves open need for longer-term comparative data.
BACKGROUND: We sought to evaluate the mid-term results of a repair-oriented strategy of the aortic valve in children. METHODS: Between February 2007 and November 2011, we performed 39 aortic valve repairs in children. Median age and weight at surgery were 5.5 years (3 days-18 years) and 16.7 kg (2.7-83.5), respectively. A total of 11 (28%) patients had one or more prior surgical or interventional cardiologic procedures. Median intensive care unit and hospital stay were two (1-96) and five (3-96) days, respectively. Median and cumulative follow-up were 12.7 months (15 days-64 months) and 48.9 patient-years, respectively. RESULTS: There were 3 (7.7%) early deaths all in patients undergoing additional complex cardiac procedures. Two (5.1%) patients required early surgical revision. Twenty-six (66%) patients had isolated or mixed aortic stenosis. The median gradient reduced from 62.4 (range 16-144) to 17.6 mm Hg (range 0-51.8), postoperatively (P = .02). At last follow-up, the median gradient remained largely unchanged at 21.1 mm Hg (0-49; P = .02). Twenty-six (66%) patients had isolated or mixed aortic valve regurgitation (mild in 8 [20%], moderate in 15 [38%], and severe in 6 ([15%] patients). The degree of aortic regurgitation improved in all patients with moderate or severe aortic regurgitation (P = .04). At last follow-up, two patients had moderate aortic regurgitation. Kaplan Meier freedom from reintervention in the survivors was 95% at three years. CONCLUSIONS: A repair-oriented strategy for the aortic valve in children has satisfactory early and mid-term results and remains a promising management option in children with aortic valve disease.
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Kandakure et al. (2014) conducted a cohort in Aortic valve disease (n=39). Repair-oriented strategy for the aortic valve was evaluated on Freedom from reintervention at 3 years. A repair-oriented strategy for the aortic valve in children achieved a 95% Kaplan-Meier freedom from reintervention at 3 years among survivors, with significant gradient reductions.
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