Key result
Complex aortic valve repair achieves ~96% discharge survival in congenital heart disease.
Why the study?
The optimal surgical strategy for aortic valve repair in young adults with congenital heart disease has not been clearly established.
Does complex aortic valve repair provide acceptable survival and freedom from reintervention in patients with congenital heart disease?
Cohort (n=28)
No
Does complex aortic valve repair provide acceptable survival and freedom from reintervention in patients with congenital heart disease?
Complex aortic valve repair in congenital patients demonstrates excellent short-to-medium term survival and acceptable freedom from reintervention, supporting its use as a first-line procedure.
May support complex aortic valve repair as initial option in congenital patients; hypothesis-generating and requires prospective validation before practice change.
Introduction In the congenital population, particularly in young adults, the best strategy for aortic valve surgery has not been clearly established. This study investigates the mortality, perioperative morbidity and echocardiographic evolution of complex aortic valve repair techniques. Material and methods We performed a retrospective monocentric descriptive study of patients operated at the Louis Pradel Hospital (Lyon) from 2017 to 2023. We included patients operated for complex aortic valve repair by the congenital heart surgery team, excluding simple commissurotomies. The primary endpoint was postoperative survival. The secondary endpoints were freedom from surgical reintervention and echocardiographic evolution of aortic regurgitation, aortic stenosis and annular diameter. The analysis was performed using Kaplan Meier methods. Results Twenty-eight patients were included. The mean age was 11.1 years (range 1–35 years) and the mean weight was 37.5 kg (range 8.2–79 kg). The postoperative survival rate was 96.4% at discharge (27/28 patients). The mean follow-up interval was 35 months (range 14–79 months). At the end of the follow-up, the freedom from reoperation was 85.7%. Four patients underwent reoperation for worsening aortic valve and/or ventricular function (1 heart transplantation, 2 Ross procedures, 1 aortic valve replacement). Results on secondary endpoints showed a trend towards improvement in annular diameter postoperatively between pre- and postoperative echocardiography for each patient, with no statistically significant difference for aortic insufficiency, but for aortic stenosis (p = 0.02). Conclusion This study shows an excellent survival rate, and a similar risk of reintervention compared with literature data. All the data described above argue in favor of an aortic valve repair surgery as a first line procedure in case of congenital heart disease.
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Bulescu et al. (2024) conducted a cohort in Congenital aortic valve disease (n=28). Complex aortic valve repair was evaluated on Postoperative survival at discharge. Complex aortic valve repair in congenital patients resulted in a 96.4% postoperative survival rate at discharge and 85.7% freedom from reoperation at 3 years.
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